• Target：
• PPP1R14D

• Gene Name：
• PPP1R14D

• Protein Name：
• Protein phosphatase 1 regulatory subunit 14D

• Human Gene Id：
• 54866

• Human Swiss Prot No：
• Q9NXH3

• Mouse Swiss Prot No：
• Q7TT52

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PPP1R14D. AA range:66-115

• Specificity：
• PPP1R14D Polyclonal Antibody detects endogenous levels of PPP1R14D protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PPP1R14D;GBPI;Protein phosphatase 1 regulatory subunit 14D;Gastrointestinal and brain-specific PP1-inhibitory protein 1;GBPI-1

• Observed Band(KD)：
• 24kD

• Background：
• Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010],

• Function：
• function:Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,PTM:Phosphorylated on several residues.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Detected in colon, intestine, kidney and brain cortex.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Detected in colon, intestine, kidney and brain cortex.

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