PMS2/PMS2CL Polyclonal Antibody

    • Catalog No.:YT3805
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • PMS2/PMS2CL
      • Gene Name:
      • PMS2/PMS2CL
      • Protein Name:
      • Mismatch repair endonuclease PMS2/Protein PMS2CL
      • Human Gene Id:
      • 5395
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
      • Specificity:
      • PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • PMS2CL;Protein PMS2CL;PMS2-C terminal-like protein;PMS2;PMSL2;Mismatch repair endonuclease PMS2;DNA mismatch repair protein PMS2;PMS1 protein homolog 2
      • Molecular Weight(Da):
      • 21kD
      • Background:
      • caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
      • Function:
      • caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
      • Subcellular Location:
      • mismatch repair complex,
      • Expression:
      • Fetal brain,Testis,
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PMS2/PMS2CL Antibody. The picture on the right is blocked with the synthesized peptide.