• Target：
• PLA1A

• Fields：
• >>Glycerophospholipid metabolism;>>Ras signaling pathway

• Gene Name：
• PLA1A

• Protein Name：
• Phospholipase A1 member A

• Human Gene Id：
• 51365

• Human Swiss Prot No：
• Q53H76

• Mouse Swiss Prot No：
• Q8VI78

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PLA1A. AA range:381-430

• Specificity：
• PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PLA1A;NMD;PSPLA1;Phospholipase A1 member A;Phosphatidylserine-specific phospholipase A1;PS-PLA1

• Observed Band(KD)：
• 45-50kD

• Background：
• The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],

• Function：
• function:Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,tissue specificity:Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.,

• Subcellular Location：
• Secreted .

• Expression：
• Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.

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