PITPβ Polyclonal Antibody
- Catalog No.:YT3738
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- PITPβ
- Gene Name:
- PITPNB
- Protein Name:
- Phosphatidylinositol transfer protein beta isoform
- Human Gene Id:
- 23760
- Human Swiss Prot No:
- P48739
- Mouse Gene Id:
- 56305
- Mouse Swiss Prot No:
- P53811
- Rat Gene Id:
- 114561
- Rat Swiss Prot No:
- P53812
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human PITPNB. AA range:20-69
- Specificity:
- PITPβ Polyclonal Antibody detects endogenous levels of PITPβ protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- PITPNB;Phosphatidylinositol transfer protein beta isoform;PI-TP-beta;PtdIns transfer protein beta;PtdInsTP beta
- Observed Band(KD):
- 32kD
- Background:
- This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013],
- Function:
- function:Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.,PTM:Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.,similarity:Belongs to the PtdIns transfer protein family. Class I subfamily.,tissue specificity:Widely expressed in various tissues including brain.,
- Subcellular Location:
- Golgi apparatus . Golgi apparatus membrane . Endoplasmic reticulum membrane .
- Expression:
- Widely expressed in various tissues including brain.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using PITPβ Polyclonal Antibody diluted at 1:2000
- Western Blot analysis of HepG2 cells using PITPβ Polyclonal Antibody diluted at 1:2000
- Western blot analysis of lysates from HepG2 cells, using PITPNB Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from K562 cells using PITPNB antibody.
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).