PIG-H Polyclonal Antibody
- Catalog No.:YT3725
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- PIG-H
- Fields:
- >>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways
- Gene Name:
- PIGH
- Protein Name:
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
- Human Gene Id:
- 5283
- Human Swiss Prot No:
- Q14442
- Mouse Gene Id:
- 110417
- Mouse Swiss Prot No:
- Q5M9N4
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human PIGH. AA range:137-186
- Specificity:
- PIG-H Polyclonal Antibody detects endogenous levels of PIG-H protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- PIGH;Phosphatidylinositol N-acetylglucosaminyltransferase subunit H;Phosphatidylinositol-glycan biosynthesis class H protein;PIG-H
- Molecular Weight(Da):
- 21kD
- Background:
- This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGH family.,subunit:Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity.,
- Subcellular Location:
- Cytoplasm.
- Expression:
- Blood,Lung,Placenta,
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- Antibody-FAQs
- Products Images
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PIGH Antibody. The picture on the right is blocked with the synthesized peptide.