PI-9 Polyclonal Antibody

    • Catalog No.:YT3716
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • PI-9
      • Fields:
      • >>Amoebiasis
      • Gene Name:
      • SERPINB9
      • Protein Name:
      • Serpin B9
      • Human Gene Id:
      • 5272
      • Human Swiss Prot No:
      • P50453
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SERPINB9. AA range:241-290
      • Specificity:
      • PI-9 Polyclonal Antibody detects endogenous levels of PI-9 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SERPINB9;PI9;Serpin B9;Cytoplasmic antiproteinase 3;CAP-3;CAP3;Peptidase inhibitor 9;PI-9
      • Observed Band(KD):
      • 40kD
      • Background:
      • This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012],
      • Function:
      • function:Granzyme B inhibitor.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,
      • Subcellular Location:
      • Cytoplasm.
      • Expression:
      • Bone marrow,Human esophagus tumor,Placenta,Testis,
      • Products Images
      • Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
      • Western Blot analysis of various cells using PI-9 Polyclonal Antibody diluted at 1:1000
      • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using SERPINB9 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from COLO, HUVEC, and Jurkat cells, using SERPINB9 Antibody. The lane on the right is blocked with the synthesized peptide.