• Target：
• PGD

• Fields：
• >>Pentose phosphate pathway;>>Glutathione metabolism;>>Metabolic pathways;>>Carbon metabolism

• Gene Name：
• PGD

• Protein Name：
• 6-phosphogluconate dehydrogenase decarboxylating

• Human Gene Id：
• 5226

• Human Swiss Prot No：
• P52209

• Mouse Gene Id：
• 110208

• Mouse Swiss Prot No：
• Q9DCD0

• Rat Gene Id：
• 1.0036e+008

• Rat Swiss Prot No：
• P85968

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120

• Specificity：
• PGD Polyclonal Antibody detects endogenous levels of PGD protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PGD;PGDH;6-phosphogluconate dehydrogenase; decarboxylating

• Observed Band(KD)：
• 40kD

• Background：
• 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],

• Function：
• catalytic activity:6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.,similarity:Belongs to the 6-phosphogluconate dehydrogenase family.,subunit:Homodimer.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Heart,Lung,

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