PABP3 Polyclonal Antibody

    • Catalog No.:YT3563
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human
      • Target:
      • PABP3
      • Fields:
      • >>mRNA surveillance pathway;>>RNA degradation
      • Gene Name:
      • PABPC3
      • Protein Name:
      • Polyadenylate-binding protein 3
      • Human Gene Id:
      • 5042
      • Human Swiss Prot No:
      • Q9H361
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401
      • Specificity:
      • PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000.IHC:1:50-300 ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • PABPC3;PABP3;PABPL3;Polyadenylate-binding protein 3;PABP-3;Poly(A)-binding protein 3;Testis-specific poly(A)-binding protein
      • Observed Band(KD):
      • 70kD
      • Background:
      • Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],
      • Function:
      • function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Testis specific.
      • Products Images
      • Western Blot analysis of 3T3 cells using PABP3 Polyclonal Antibody
      • Western blot analysis of PABPC3 Antibody. The lane on the right is blocked with the PABPC3 peptide.
      • Immunohistochemistryt analysis of paraffin-embedded human testis, using PABPC3 Antibody. The lane on the right is blocked with the PABPC3 peptide.