• Target：
• OTUB2

• Gene Name：
• OTUB2

• Protein Name：
• Ubiquitin thioesterase OTUB2

• Human Gene Id：
• 78990

• Human Swiss Prot No：
• Q96DC9

• Mouse Gene Id：
• 68149

• Mouse Swiss Prot No：
• Q9CQX0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182

• Specificity：
• OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• OTUB2;C14orf137;OTB2;OTU2;Ubiquitin thioesterase OTUB2;Deubiquitinating enzyme OTUB2;OTU domain-containing ubiquitin aldehyde-binding protein 2;Otubain-2;Ubiquitin-specific-processing protease OTUB2

• Observed Band(KD)：
• 27kD

• Background：
• OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],

• Function：
• function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,

• Subcellular Location：
• nucleus,

• Expression：
• Widely expressed. Expressed at higher level in brain.

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