• Target：
• Orexin R-1

• Fields：
• >>Neuroactive ligand-receptor interaction

• Gene Name：
• HCRTR1

• Protein Name：
• Orexin receptor type 1

• Human Gene Id：
• 3061

• Human Swiss Prot No：
• O43613

• Mouse Gene Id：
• 230777

• Mouse Swiss Prot No：
• P58307

• Rat Gene Id：
• 25593

• Rat Swiss Prot No：
• P56718

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human HCRTR1. AA range:231-280

• Specificity：
• Orexin R-1 Polyclonal Antibody detects endogenous levels of Orexin R-1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HCRTR1;Orexin receptor type 1;Ox-1-R;Ox1-R;Ox1R;Hypocretin receptor type 1

• Observed Band(KD)：
• 50kD

• Background：
• The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],

• Function：
• function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Brain,

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