• Target：
• OCT3

• Fields：
• >>Choline metabolism in cancer

• Gene Name：
• SLC22A3

• Protein Name：
• Solute carrier family 22 member 3

• Human Gene Id：
• 6581

• Human Swiss Prot No：
• O75751

• Mouse Swiss Prot No：
• Q9WTW5

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SLC22A3. AA range:275-324

• Specificity：
• OCT3 Polyclonal Antibody detects endogenous levels of 40819 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SLC22A3;EMTH;OCT3;Solute carrier family 22 member 3;Extraneuronal monoamine transporter;EMT;Organic cation transporter 3

• Observed Band(KD)：
• 61kD

• Background：
• Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008],

• Function：
• function:Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,tissue specificity:Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.,

• Subcellular Location：
• Membrane; Multi-pass membrane protein.

• Expression：
• Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.

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