OB-cadherin Polyclonal Antibody
- Catalog No.:YT3224
- Applications:WB;ELISA
- Reactivity:Human;Mouse
- Target:
- OB-cadherin
- Gene Name:
- CDH11
- Protein Name:
- Cadherin-11
- Human Gene Id:
- 1009
- Human Swiss Prot No:
- P55287
- Mouse Gene Id:
- 12552
- Mouse Swiss Prot No:
- P55288
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470
- Specificity:
- OB-cadherin Polyclonal Antibody detects endogenous levels of OB-cadherin protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CDH11;Cadherin-11;OSF-4;Osteoblast cadherin;OB-cadherin
- Observed Band(KD):
- 85kD
- Background:
- This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],
- Function:
- function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.,
- Subcellular Location:
- Cell membrane; Single-pass type I membrane protein.
- Expression:
- Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.
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- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
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- FLOW-CYTOMEYRT-PROTOCOL
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- July 13-2018
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- July 13-2018
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- July 13-2018
- Antibody-FAQs
- Products Images
- Western Blot analysis of Jurkat cells using OB-cadherin Polyclonal Antibody
- Western blot analysis of lysates from Jurkat cells, using CDH11 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using Cytochrome P450 1A1/2 antibody.