OATP1 Polyclonal Antibody

    • Catalog No.:YT3221
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human
      • Target:
      • OATP1
      • Fields:
      • >>Bile secretion
      • Gene Name:
      • SLCO1A2
      • Protein Name:
      • Solute carrier organic anion transporter family member 1A2
      • Human Gene Id:
      • 6579
      • Human Swiss Prot No:
      • P46721
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300
      • Specificity:
      • OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SLCO1A2;OATP;OATP1;OATP1A2;SLC21A3;Solute carrier organic anion transporter family member 1A2;OATP-A;Organic anion-transporting polypeptide 1;OATP-1;Sodium-independent organic anion transporter;Solute carrier family 21 member 3
      • Observed Band(KD):
      • 80kD
      • Background:
      • This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],
      • Function:
      • function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • Brain,Liver,Teratocarcinoma,
      • Products Images
      • Western Blot analysis of various cells using OATP1 Polyclonal Antibody diluted at 1:2000
      • Western Blot analysis of A549 AD293 HEPG2 using OATP1 Polyclonal Antibody. Antibody was diluted at 1:2000
      • Western blot analysis of lysates from HeLa, MCF-7, and HepG2 cells, using SLCO1A2 Antibody. The lane on the right is blocked with the synthesized peptide.