OATP1 Polyclonal Antibody
- Catalog No.:YT3221
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human
- Target:
- OATP1
- Fields:
- >>Bile secretion
- Gene Name:
- SLCO1A2
- Protein Name:
- Solute carrier organic anion transporter family member 1A2
- Human Gene Id:
- 6579
- Human Swiss Prot No:
- P46721
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300
- Specificity:
- OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SLCO1A2;OATP;OATP1;OATP1A2;SLC21A3;Solute carrier organic anion transporter family member 1A2;OATP-A;Organic anion-transporting polypeptide 1;OATP-1;Sodium-independent organic anion transporter;Solute carrier family 21 member 3
- Observed Band(KD):
- 80kD
- Background:
- This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],
- Function:
- function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
- Expression:
- Brain,Liver,Teratocarcinoma,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using OATP1 Polyclonal Antibody diluted at 1:2000
- Western Blot analysis of A549 AD293 HEPG2 using OATP1 Polyclonal Antibody. Antibody was diluted at 1:2000
- Western blot analysis of lysates from HeLa, MCF-7, and HepG2 cells, using SLCO1A2 Antibody. The lane on the right is blocked with the synthesized peptide.