NRBF-2 Polyclonal Antibody
- Catalog No.:YT3187
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- NRBF-2
- Fields:
- >>Autophagy - animal;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
- Gene Name:
- NRBF2
- Protein Name:
- Nuclear receptor-binding factor 2
- Human Gene Id:
- 29982
- Human Swiss Prot No:
- Q96F24
- Mouse Gene Id:
- 641340
- Mouse Swiss Prot No:
- Q8VCQ3
- Rat Gene Id:
- 58839
- Rat Swiss Prot No:
- Q9QYK3
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NRBF2. AA range:140-189
- Specificity:
- NRBF-2 Polyclonal Antibody detects endogenous levels of NRBF-2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- NRBF2;COPR;Nuclear receptor-binding factor 2;NRBF-2;Comodulator of PPAR and RXR
- Observed Band(KD):
- 36kD
- Background:
- function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
- Function:
- function:May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).,subunit:Interacts with PPARA, PPARD and PPARG. Interacts with RARA, RARG and RXRA in the presence of bound ligand.,tissue specificity:Detected in keratinocytes, liver and placenta.,
- Subcellular Location:
- Nucleus . Cytoplasm . Cytoplasmic vesicle . Cytoplasmic vesicle, autophagosome .
- Expression:
- Detected in keratinocytes, liver and placenta (PubMed:15610520). Expressed in a subset of cells in pediatric medulloblastoma (PubMed:18619852).
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using NRBF-2 Polyclonal Antibody
- Western blot analysis of lysates from A549 cells, using NRBF2 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from RAW264.7cells using NRBF2 antibody.