NPY2-R Polyclonal Antibody

    • Catalog No.:YT3184
    • Applications:WB;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • NPY2-R
      • Fields:
      • >>Neuroactive ligand-receptor interaction
      • Gene Name:
      • NPY2R
      • Protein Name:
      • Neuropeptide Y receptor type 2
      • Human Gene Id:
      • 4887
      • Human Swiss Prot No:
      • P49146
      • Mouse Swiss Prot No:
      • P97295
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human NPY2R. AA range:1-50
      • Specificity:
      • NPY2-R Polyclonal Antibody detects endogenous levels of NPY2-R protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NPY2R;Neuropeptide Y receptor type 2;NPY2-R;NPY-Y2 receptor;Y2 receptor
      • Observed Band(KD):
      • 43kD
      • Background:
      • function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,
      • Function:
      • function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
      • Products Images
      • Western Blot analysis of various cells using NPY2-R Polyclonal Antibody diluted at 1:500
      • Western Blot analysis of HT29 cells using NPY2-R Polyclonal Antibody diluted at 1:500
      • Immunofluorescence analysis of A549 cells, using NPY2R Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HepG2 cells, using NPY2R Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HUVECcells using NPY2R antibody.