• Target：
• NOC2L

• Gene Name：
• NOC2L

• Protein Name：
• Nucleolar complex protein 2 homolog

• Human Gene Id：
• 26155

• Human Swiss Prot No：
• Q9Y3T9

• Mouse Swiss Prot No：
• Q9WV70

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651

• Specificity：
• NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NOC2L;NIR;Nucleolar complex protein 2 homolog;Protein NOC2 homolog;NOC2-like protein;Novel INHAT repressor

• Observed Band(KD)：
• 85kD

• Background：
• NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008],

• Function：
• similarity:Belongs to the NOC2 family.,

• Subcellular Location：
• Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.

• Expression：
• Brain,Epithelium,Placenta,

Age-Associated Proteomic Signatures and Potential Clinically Actionable Targets of Colorectal Cancer. MOLECULAR & CELLULAR PROTEOMICS Mol Cell Proteomics. 2021 Jan;20:100115 WB Human 1:2000 Colorectal cancer (CRC) tissues HT29,HCT116

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