NMBR Polyclonal Antibody
- Catalog No.:YT3148
- Applications:WB;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- NMBR
- Fields:
- >>Neuroactive ligand-receptor interaction
- Gene Name:
- NMBR
- Protein Name:
- Neuromedin-B receptor
- Human Gene Id:
- 4829
- Human Swiss Prot No:
- P28336
- Mouse Gene Id:
- 18101
- Mouse Swiss Prot No:
- O54799
- Rat Gene Id:
- 25264
- Rat Swiss Prot No:
- P24053
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270
- Specificity:
- NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- NMBR;Neuromedin-B receptor;NMB-R;Epididymis tissue protein Li 185a;Neuromedin-B-preferring bombesin receptor
- Observed Band(KD):
- 43kD
- Background:
- This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
- Function:
- function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein .
- Expression:
- Expressed in epididymis (at protein level).
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- Antibody-FAQs
- Products Images
- Western Blot analysis of 293 cells using NMBR Polyclonal Antibody
- Immunofluorescence analysis of A549 cells, using NMBR Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from 293 and Jurkat cells, using NMBR Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of 1) Human Brain Tissue, 2) Rat Brain Tissue using NMBR Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using NMBR Polyclonal Antibody.