• Target：
• NMBR

• Fields：
• >>Neuroactive ligand-receptor interaction

• Gene Name：
• NMBR

• Protein Name：
• Neuromedin-B receptor

• Human Gene Id：
• 4829

• Human Swiss Prot No：
• P28336

• Mouse Gene Id：
• 18101

• Mouse Swiss Prot No：
• O54799

• Rat Gene Id：
• 25264

• Rat Swiss Prot No：
• P24053

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

• Specificity：
• NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NMBR;Neuromedin-B receptor;NMB-R;Epididymis tissue protein Li 185a;Neuromedin-B-preferring bombesin receptor

• Observed Band(KD)：
• 43kD

• Background：
• This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

• Function：
• function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Expressed in epididymis (at protein level).

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