• Target：
• Nkx-6.1

• Fields：
• >>Maturity onset diabetes of the young

• Gene Name：
• NKX6-1

• Protein Name：
• Homeobox protein Nkx-6.1

• Human Gene Id：
• 4825

• Human Swiss Prot No：
• P78426

• Mouse Gene Id：
• 18096

• Mouse Swiss Prot No：
• Q99MA9

• Rat Gene Id：
• 65193

• Rat Swiss Prot No：
• O35762

• Immunogen：
• Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260

• Specificity：
• Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NKX6-1;NKX6A;Homeobox protein Nkx-6.1;Homeobox protein NK-6 homolog A

• Molecular Weight(Da)：
• 38kD

• Background：
• In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],

• Function：
• function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells.,

• Subcellular Location：
• Nucleus .

• Expression：
• Pancreatic beta cells.

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