NK-TR Polyclonal Antibody

    • Catalog No.:YT3137
    • Applications:IHC;IF;WB;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • NK-TR
      • Gene Name:
      • NKTR
      • Protein Name:
      • NK-tumor recognition protein
      • Human Gene Id:
      • 4820
      • Human Swiss Prot No:
      • P30414
      • Mouse Swiss Prot No:
      • P30415
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human NKTR. AA range:784-833
      • Specificity:
      • NK-TR Polyclonal Antibody detects endogenous levels of NK-TR protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NKTR;NK-tumor recognition protein;NK-TR protein;Natural-killer cells cyclophilin-related protein
      • Molecular Weight(Da):
      • 166kD
      • Background:
      • This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008],
      • Function:
      • catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:Component of a putative tumor-recognition complex. Involved in the function of NK cells.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Attached to the membrane via its N-terminus.,
      • Subcellular Location:
      • Cell membrane .
      • Expression:
      • Aorta endothelial cell,Blood,Epithelium,Fetal kidney,Human endometr
      • Products Images
      • Immunofluorescence analysis of HeLa cells, using NKTR Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NKTR Antibody. The picture on the right is blocked with the synthesized peptide.