• Target：
• NKp46

• Fields：
• >>Natural killer cell mediated cytotoxicity

• Gene Name：
• NCR1

• Protein Name：
• Natural cytotoxicity triggering receptor 1

• Human Gene Id：
• 9437

• Human Swiss Prot No：
• O76036

• Mouse Swiss Prot No：
• Q8C567

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194

• Specificity：
• NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NCR1;LY94;Natural cytotoxicity triggering receptor 1;Lymphocyte antigen 94 homolog;NK cell-activating receptor;Natural killer cell p46-related protein;NK-p46;NKp46;hNKp46;CD antigen CD335

• Observed Band(KD)：
• 40kD

• Background：
• function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,

• Function：
• function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein .

• Expression：
• Selectively expressed by both resting and activated NK cells.

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