• Target：
• NK-3R

• Fields：
• >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction

• Gene Name：
• TACR3

• Protein Name：
• Neuromedin-K receptor

• Human Gene Id：
• 6870

• Human Swiss Prot No：
• P29371

• Mouse Gene Id：
• 21338

• Mouse Swiss Prot No：
• P47937

• Rat Gene Id：
• 24808

• Rat Swiss Prot No：
• P16177

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NK3R. AA range:401-450

• Specificity：
• NK-3R Polyclonal Antibody detects endogenous levels of NK-3R protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TACR3;NK3R;TAC3R;Neuromedin-K receptor;NKR;NK-3 receptor;NK-3R;Neurokinin B receptor;Tachykinin receptor 3

• Observed Band(KD)：
• 52kD

• Background：
• This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008],

• Function：
• function:This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,miscellaneous:The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.,PTM:The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain,G-protein coupled receptors,PCR rescued clones,Placenta,

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