• Target：
• NK-1R

• Fields：
• >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction

• Gene Name：
• TACR1

• Protein Name：
• Substance-P receptor

• Human Gene Id：
• 6869

• Human Swiss Prot No：
• P25103

• Mouse Gene Id：
• 21336

• Mouse Swiss Prot No：
• P30548

• Rat Gene Id：
• 24807

• Rat Swiss Prot No：
• P14600

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NK1R. AA range:211-260

• Specificity：
• NK-1R Polyclonal Antibody detects endogenous levels of NK-1R protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TACR1;NK1R;TAC1R;Substance-P receptor;SPR;NK-1 receptor;NK-1R;Tachykinin receptor 1

• Observed Band(KD)：
• 50kD

• Background：
• This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008],

• Function：
• function:This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.,online information:Tachykinin entry,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain,G-protein coupled receptors,Lung,Placenta,

He-Wei granules inhibit chemotherapy-induced vomiting (CINV) in rats by reducing oxidative stress and regulating 5-HT, substance P, ghrelin and obestatin. RSC Advances Rsc Adv. 2017 Sep;7(69):43866-43878 WB Rat ileum , medulla oblongata

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs