• Target：
• Neurocalcin δ

• Fields：
• >>Olfactory transduction

• Gene Name：
• NCALD

• Protein Name：
• Neurocalcin-delta

• Human Gene Id：
• 83988

• Human Swiss Prot No：
• P61601

• Mouse Gene Id：
• 52589

• Mouse Swiss Prot No：
• Q91X97

• Rat Gene Id：
• 553106

• Rat Swiss Prot No：
• Q5PQN0

• Immunogen：
• Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450

• Specificity：
• Neurocalcin δ Polyclonal Antibody detects endogenous levels of Neurocalcin δ protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NCALD;Neurocalcin-delta

• Molecular Weight(Da)：
• 22kD

• Background：
• This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

• Function：
• function:May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,tissue specificity:Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.,

• Subcellular Location：
• intracellular,cytosol,clathrin coat of trans-Golgi network vesicle,extracellular exosome,

• Expression：
• Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.

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