NDUFS3 Polyclonal Antibody

  • Catalog No.：YT3018
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse
    • Target：
    • NDUFS3
    • Fields：
    • >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
    • Gene Name：
    • NDUFS3
    • Protein Name：
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial
    • Human Gene Id：
    • 4722
    • Human Swiss Prot No：
    • O75489
    • Mouse Swiss Prot No：
    • Q9DCT2
    • Immunogen：
    • The antiserum was produced against synthesized peptide derived from human NDUFS3. AA range:117-166
    • Specificity：
    • NDUFS3 Polyclonal Antibody detects endogenous levels of NDUFS3 protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • NDUFS3;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial;Complex I-30kD;CI-30kD;NADH-ubiquinone oxidoreductase 30 kDa subunit
    • Observed Band(KD)：
    • 40kD
    • Background：
    • This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009],
    • Function：
    • catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits.,
    • Subcellular Location：
    • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
    • Expression：
    • Brain,Cajal-Retzius cell,Pituitary,Skin,Stomach mucosa,Uter

    Attributes

    • Code：
    • YT3018
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-12-24
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