NDUFC1 Polyclonal Antibody
- Catalog No.:YT3015
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- NDUFC1
- Fields:
- >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
- Gene Name:
- NDUFC1
- Protein Name:
- NADH dehydrogenase [ubiquinone] 1 subunit C1 mitochondrial
- Human Gene Id:
- 4717
- Human Swiss Prot No:
- O43677
- Mouse Gene Id:
- 66377
- Mouse Swiss Prot No:
- Q9CQY9
- Immunogen:
- Synthesized peptide derived from NDUFC1 . at AA range: 40-120
- Specificity:
- NDUFC1 Polyclonal Antibody detects endogenous levels of NDUFC1 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- NDUFC1;NADH dehydrogenase [ubiquinone] 1 subunit C1; mitochondrial;Complex I-KFYI;CI-KFYI;NADH-ubiquinone oxidoreductase KFYI subunit
- Molecular Weight(Da):
- 9kD
- Background:
- The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
- Function:
- function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC1 subunit family.,subunit:Complex I is composed of 45 different subunits.,
- Subcellular Location:
- Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
- Expression:
- Brain,Heart,Skin,Umbilical cord blood,
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).