NDUFC1 Polyclonal Antibody

    • Catalog No.:YT3015
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • NDUFC1
      • Fields:
      • >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
      • Gene Name:
      • NDUFC1
      • Protein Name:
      • NADH dehydrogenase [ubiquinone] 1 subunit C1 mitochondrial
      • Human Gene Id:
      • 4717
      • Human Swiss Prot No:
      • O43677
      • Mouse Swiss Prot No:
      • Q9CQY9
      • Immunogen:
      • Synthesized peptide derived from NDUFC1 . at AA range: 40-120
      • Specificity:
      • NDUFC1 Polyclonal Antibody detects endogenous levels of NDUFC1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • NDUFC1;NADH dehydrogenase [ubiquinone] 1 subunit C1; mitochondrial;Complex I-KFYI;CI-KFYI;NADH-ubiquinone oxidoreductase KFYI subunit
      • Molecular Weight(Da):
      • 9kD
      • Background:
      • The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
      • Function:
      • function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC1 subunit family.,subunit:Complex I is composed of 45 different subunits.,
      • Subcellular Location:
      • Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
      • Expression:
      • Brain,Heart,Skin,Umbilical cord blood,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).