• Target：
• NDUFB9

• Fields：
• >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy

• Gene Name：
• NDUFB9

• Protein Name：
• NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

• Human Gene Id：
• 4715

• Human Swiss Prot No：
• Q9Y6M9

• Mouse Swiss Prot No：
• Q9CQJ8

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NDUFB9. AA range:102-151

• Specificity：
• NDUFB9 Polyclonal Antibody detects endogenous levels of NDUFB9 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NDUFB9;LYRM3;UQOR22;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9;Complex I-B22;CI-B22;LYR motif-containing protein 3;NADH-ubiquinone oxidoreductase B22 subunit

• Observed Band(KD)：
• 22kD

• Background：
• The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],

• Function：
• function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I LYR family.,subunit:Mammalian complex I is composed of 45 different subunits.,

• Subcellular Location：
• Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

• Expression：
• Astrocytoma,Brain,Colon adenocarcinoma,Kidney,Placenta,Umbi

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