• Target：
• NCoA-7

• Fields：
• >>Lysosome

• Gene Name：
• NCOA7

• Protein Name：
• Nuclear receptor coactivator 7

• Human Gene Id：
• 135112

• Human Swiss Prot No：
• Q8NI08

• Mouse Swiss Prot No：
• Q6DFV7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471

• Specificity：
• NCoA-7 Polyclonal Antibody detects endogenous levels of NCoA-7 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NCOA7;ERAP140;ESNA1;Nbla00052;Nbla10993;Nuclear receptor coactivator 7;140 kDa estrogen receptor-associated protein;Estrogen nuclear receptor coactivator 1

• Observed Band(KD)：
• 106kD

• Background：
• function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,

• Function：
• function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,

• Subcellular Location：
• Nucleus .

• Expression：
• Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.

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