• Target：
• NCKX3

• Gene Name：
• SLC24A3

• Protein Name：
• Sodium/potassium/calcium exchanger 3

• Human Gene Id：
• 57419

• Human Swiss Prot No：
• Q9HC58

• Mouse Swiss Prot No：
• Q99PD7

• Rat Swiss Prot No：
• Q9EPQ0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SLC24A3. AA range:354-403

• Specificity：
• NCKX3 Polyclonal Antibody detects endogenous levels of NCKX3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SLC24A3;NCKX3;Sodium/potassium/calcium exchanger 3;Na(+)/K(+)/Ca(2+)-exchange protein 3;Solute carrier family 24 member 3

• Observed Band(KD)：
• 60kD

• Background：
• Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008],

• Function：
• function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specificity:Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Abundant in the brain (PubMed:11294880). Expressed at low levels in the aorta, uterus and intestine (PubMed:11294880).

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