MRGX3 Polyclonal Antibody

    • Catalog No.:YT2836
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • MRGX3
      • Gene Name:
      • MRGPRX3
      • Protein Name:
      • Mas-related G-protein coupled receptor member X3
      • Human Swiss Prot No:
      • Q96LB0
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human MRGX3. AA range:99-148
      • Specificity:
      • MRGX3 Polyclonal Antibody detects endogenous levels of MRGX3 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • MRGPRX3;MRGX3;SNSR1;SNSR2;Mas-related G-protein coupled receptor member X3;Sensory neuron-specific G-protein coupled receptor 1/2
      • Observed Band(KD):
      • 34kD
      • Background:
      • This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009],
      • Function:
      • function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
      • Subcellular Location:
      • Cell membrane; Multi-pass membrane protein.
      • Expression:
      • Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
      • Products Images
      • Western Blot analysis of K562 cells using MRGX3 Polyclonal Antibody
      • Immunofluorescence analysis of MCF7 cells, using MRGX3 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from K562 cells, using MRGX3 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from 293 cells using MRGX3 antibody.
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).