• Target：
• MRGX1

• Gene Name：
• MRGPRX1

• Protein Name：
• Mas-related G-protein coupled receptor member X1

• Human Gene Id：
• 259249

• Human Swiss Prot No：
• Q96LB2

• Mouse Swiss Prot No：
• Q8CIP3

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

• Specificity：
• MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MRGPRX1;MRGX1;SNSR3;SNSR4;Mas-related G-protein coupled receptor member X1;Sensory neuron-specific G-protein coupled receptor 3/4

• Observed Band(KD)：
• 36kD

• Background：
• function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,

• Function：
• function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

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