• Target：
• MEF-2

• Fields：
• >>cGMP-PKG signaling pathway;>>Apelin signaling pathway

• Gene Name：
• MEF2B

• Protein Name：
• Myocyte-specific enhancer factor 2B

• Human Gene Id：
• 4207

• Human Swiss Prot No：
• Q02080

• Mouse Swiss Prot No：
• O55087

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100

• Specificity：
• MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MEF2B;XMEF2;Myocyte-specific enhancer factor 2B;RSRFR2;Serum response factor-like protein 2

• Observed Band(KD)：
• 38kD

• Background：
• This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010],

• Function：
• function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain.,

• Subcellular Location：
• Nucleus.

• Expression：
• Expressed in skeletal and cardiac muscle and brain.

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