MC5-R Polyclonal Antibody
- Catalog No.:YT2676
- Applications:WB;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- MC5-R
- Fields:
- >>Neuroactive ligand-receptor interaction
- Gene Name:
- MC5R
- Protein Name:
- Melanocortin receptor 5
- Human Gene Id:
- 4161
- Human Swiss Prot No:
- P33032
- Mouse Swiss Prot No:
- P41149
- Rat Gene Id:
- 25726
- Rat Swiss Prot No:
- P35345
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MC5R. AA range:271-320
- Specificity:
- MC5-R Polyclonal Antibody detects endogenous levels of MC5-R protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- MC5R;Melanocortin receptor 5;MC5-R;MC-2
- Observed Band(KD):
- 40kD
- Background:
- This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010],
- Function:
- function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in the brain but not in the melanoma cells.,
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
- Expression:
- Expressed in the brain but not in the melanoma cells.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using MC5-R Polyclonal Antibody
- Western Blot analysis of 3T3 cells using MC5-R Polyclonal Antibody
- Immunofluorescence analysis of MCF7 cells, using MC5R Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from K562 cells, using MC5R Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using MC5R antibody.
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).