• Target：
• Lyl-1

• Fields：
• >>Transcriptional misregulation in cancer

• Gene Name：
• LYL1

• Protein Name：
• Protein lyl-1

• Human Gene Id：
• 4066

• Human Swiss Prot No：
• P12980

• Mouse Gene Id：
• 17095

• Mouse Swiss Prot No：
• P27792

• Rat Gene Id：
• 304663

• Rat Swiss Prot No：
• Q66HH3

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human Lyl-1. AA range:151-200

• Specificity：
• Lyl-1 Polyclonal Antibody detects endogenous levels of Lyl-1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LYL1;BHLHA18;Protein lyl-1;Class A basic helix-loop-helix protein 18;bHLHa18;Lymphoblastic leukemia-derived sequence 1

• Molecular Weight(Da)：
• 29kD

• Background：
• This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010],

• Function：
• disease:A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,

• Subcellular Location：
• Nucleus .

• Expression：
• Lymph,

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