L-type Ca++ CP γ7 Polyclonal Antibody
- Catalog No.:YT2600
- Applications:WB;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- L-type Ca++ CP γ7
- Fields:
- >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
- Gene Name:
- CACNG7
- Protein Name:
- Voltage-dependent calcium channel gamma-7 subunit
- Human Gene Id:
- 59284
- Human Swiss Prot No:
- P62955
- Mouse Gene Id:
- 81904
- Mouse Swiss Prot No:
- P62956
- Rat Gene Id:
- 140728
- Rat Swiss Prot No:
- P62957
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CACNG7. AA range:198-247
- Specificity:
- L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CACNG7;Voltage-dependent calcium channel gamma-7 subunit;Neuronal voltage-gated calcium channel gamma-7 subunit;Transmembrane AMPAR regulatory protein gamma-7;TARP gamma-7
- Observed Band(KD):
- 40kD
- Background:
- calcium voltage-gated channel auxiliary subunit gamma 7(CACNG7) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],
- Function:
- function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Widely expressed.,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein .
- Expression:
- Detected in heart left ventricle (PubMed:21127204). Widely expressed.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using L-type Ca++ CP γ7 Polyclonal Antibody diluted at 1:1000
- Western blot analysis of lysates from HepG2 cells, using CACNG7 Antibody. The lane on the right is blocked with the synthesized peptide.