L-type Ca++ CP γ7 Polyclonal Antibody

    • Catalog No.:YT2600
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • L-type Ca++ CP γ7
      • Fields:
      • >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
      • Gene Name:
      • CACNG7
      • Protein Name:
      • Voltage-dependent calcium channel gamma-7 subunit
      • Human Swiss Prot No:
      • P62955
      • Mouse Swiss Prot No:
      • P62956
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CACNG7. AA range:198-247
      • Specificity:
      • L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CACNG7;Voltage-dependent calcium channel gamma-7 subunit;Neuronal voltage-gated calcium channel gamma-7 subunit;Transmembrane AMPAR regulatory protein gamma-7;TARP gamma-7
      • Observed Band(KD):
      • 40kD
      • Background:
      • calcium voltage-gated channel auxiliary subunit gamma 7(CACNG7) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],
      • Function:
      • function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Widely expressed.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein .
      • Expression:
      • Detected in heart left ventricle (PubMed:21127204). Widely expressed.
      • Products Images
      • Western Blot analysis of various cells using L-type Ca++ CP γ7 Polyclonal Antibody diluted at 1:1000
      • Western blot analysis of lysates from HepG2 cells, using CACNG7 Antibody. The lane on the right is blocked with the synthesized peptide.