LTK Polyclonal Antibody

    • Catalog No.:YT2598
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • LTK
      • Gene Name:
      • LTK
      • Protein Name:
      • Leukocyte tyrosine kinase receptor
      • Human Gene Id:
      • 4058
      • Human Swiss Prot No:
      • P29376
      • Mouse Swiss Prot No:
      • P08923
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human LTK. AA range:206-255
      • Specificity:
      • LTK Polyclonal Antibody detects endogenous levels of LTK protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • LTK;TYK1;Leukocyte tyrosine kinase receptor;Protein tyrosine kinase 1
      • Observed Band(KD):
      • 92kD
      • Background:
      • leukocyte receptor tyrosine kinase(LTK) Homo sapiens The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
      • Function:
      • alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:The exact function of this protein is not known. It is probably a receptor with a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in non-hematopoietic cell lines and T- and B-cell lines.,
      • Subcellular Location:
      • Cell membrane ; Single-pass type I membrane protein .
      • Expression:
      • Expressed in non-hematopoietic cell lines and T- and B-cell lines.
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using LTK Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using LTK antibody.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).