LRP3 Polyclonal Antibody
- Catalog No.:YT2592
- Applications:WB;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- LRP3
- Gene Name:
- LRP3
- Protein Name:
- Low-density lipoprotein receptor-related protein 3
- Human Gene Id:
- 4037
- Human Swiss Prot No:
- O75074
- Rat Gene Id:
- 89787
- Rat Swiss Prot No:
- O88204
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66
- Specificity:
- LRP3 Polyclonal Antibody detects endogenous levels of LRP3 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- LRP3;Low-density lipoprotein receptor-related protein 3;LRP-3;105 kDa low-density lipoprotein receptor-related protein;hLRp105
- Observed Band(KD):
- 80kD
- Background:
- function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,
- Function:
- function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,
- Subcellular Location:
- Membrane ; Single-pass type I membrane protein . Membrane, coated pit .
- Expression:
- Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from RAW264.7 cells, using LRP3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).