• Target：
• LPCAT2

• Fields：
• >>Glycerophospholipid metabolism;>>Ether lipid metabolism;>>Metabolic pathways

• Gene Name：
• LPCAT2

• Protein Name：
• Lysophosphatidylcholine acyltransferase 2

• Human Gene Id：
• 54947

• Human Swiss Prot No：
• Q7L5N7

• Mouse Gene Id：
• 270084

• Mouse Swiss Prot No：
• Q8BYI6

• Rat Swiss Prot No：
• P0C1Q3

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LPCAT2. AA range:321-370

• Specificity：
• LPCAT2 Polyclonal Antibody detects endogenous levels of LPCAT2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LPCAT2;AYTL1;Lysophosphatidylcholine acyltransferase 2;LPC acyltransferase 2;LPCAT-2;LysoPC acyltransferase 2;1-acylglycerophosphocholine O-acyltransferase;1-alkylglycerophosphocholine O-acetyltransferase;Acetyl-CoA:lyso-platelet-ac

• Observed Band(KD)：
• 50kD

• Background：
• This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009],

• Function：
• catalytic activity:Acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine.,catalytic activity:Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine.,domain:The HXXXXD motif is essential for acyltransferase activity.,enzyme regulation:Acetyltransferase activity is increased following acute inflammatory stimulation by lipopolysaccharide (LPS). Acyltransferase activity is unchanged.,function:Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF pre

• Subcellular Location：
• Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus membrane ; Single-pass type II membrane protein . Cell membrane ; Single-pass type II membrane protein . Lipid droplet .

• Expression：
• Carcinoma,Fetal kidney,Kidney,

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