• Target：
• LPAAT-δ

• Fields：
• >>Glycerolipid metabolism;>>Glycerophospholipid metabolism;>>Metabolic pathways;>>Phospholipase D signaling pathway

• Gene Name：
• AGPAT4

• Protein Name：
• 1-acyl-sn-glycerol-3-phosphate acyltransferase delta

• Human Gene Id：
• 56895

• Human Swiss Prot No：
• Q9NRZ5

• Mouse Gene Id：
• 68262

• Mouse Swiss Prot No：
• Q8K4X7

• Rat Gene Id：
• 170919

• Rat Swiss Prot No：
• Q924S1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human AGPAT4. AA range:151-200

• Specificity：
• LPAAT-δ Polyclonal Antibody detects endogenous levels of LPAAT-δ protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AGPAT4;1-acyl-sn-glycerol-3-phosphate acyltransferase delta;1-acylglycerol-3-phosphate O-acyltransferase 4;1-AGP acyltransferase 4;1-AGPAT 4;Lysophosphatidic acid acyltransferase delta;LPAAT-delta

• Observed Band(KD)：
• 44kD

• Background：
• This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,function:Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein .

• Expression：
• Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.

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