LHX1 Polyclonal Antibody

    • Catalog No.:YT2559
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • LHX1
      • Gene Name:
      • LHX1
      • Protein Name:
      • LIM/homeobox protein Lhx1
      • Human Gene Id:
      • 3975
      • Human Swiss Prot No:
      • P48742
      • Mouse Swiss Prot No:
      • P63006
      • Immunogen:
      • Synthesized peptide derived from the Internal region of human LHX1.
      • Specificity:
      • LHX1 Polyclonal Antibody detects endogenous levels of LHX1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • LHX1;LIM-1;LIM1;LIM/homeobox protein Lhx1;LIM homeobox protein 1;Homeobox protein Lim-1;hLim-1
      • Observed Band(KD):
      • 44kD
      • Background:
      • This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010],
      • Function:
      • domain:The LIM domains exert a negative regulatory function and disruption of the LIM domains produces an activated form. In addition, two activation domains and a negative regulatory domain exist C-terminally to the homeobox.,function:Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,subunit:Interacts with LDB1 via the tandem LIM domains.,tissue specificity:Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Expressed in the brain, thymus, and tonsils. Expressed in samples from patients with chronic myeloid leukemia (CML) and in 58% of acute myeloid leukemia (AML) cell lines.
      • Products Images
      • Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).