• Target：
• LGR6

• Fields：
• >>Wnt signaling pathway

• Gene Name：
• LGR6

• Protein Name：
• Leucine-rich repeat-containing G-protein coupled receptor 6

• Human Gene Id：
• 59352

• Human Swiss Prot No：
• Q9HBX8

• Mouse Swiss Prot No：
• Q3UVD5

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LGR6. AA range:471-520

• Specificity：
• LGR6 Polyclonal Antibody detects endogenous levels of LGR6 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LGR6;Leucine-rich repeat-containing G-protein coupled receptor 6

• Observed Band(KD)：
• 104kD

• Background：
• This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],

• Function：
• function:Orphan receptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 16 LRR (leucine-rich) repeats.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Mammary gland,

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