• Target：
• LASS4

• Fields：
• >>Sphingolipid metabolism;>>Metabolic pathways;>>Sphingolipid signaling pathway

• Gene Name：
• CERS4

• Protein Name：
• Ceramide synthase 4

• Human Gene Id：
• 79603

• Human Swiss Prot No：
• Q9HA82

• Mouse Swiss Prot No：
• Q9D6J1

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90

• Specificity：
• LASS4 Polyclonal Antibody detects endogenous levels of LASS4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CERS4;LASS4;Ceramide synthase 4;CerS4;LAG1 longevity assurance homolog 4

• Observed Band(KD)：
• 46kD

• Background：
• function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,

• Function：
• function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein .

• Expression：
• Cerebellum,Embryo,Lung,

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