• Target：
• Ksr2

• Fields：
• >>Ras signaling pathway

• Gene Name：
• KSR2

• Protein Name：
• Kinase suppressor of Ras 2

• Human Gene Id：
• 283455

• Human Swiss Prot No：
• Q6VAB6

• Mouse Swiss Prot No：
• Q3UVC0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720

• Specificity：
• Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• KSR2;Kinase suppressor of Ras 2;hKSR2

• Observed Band(KD)：
• 108kD

• Background：
• domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,

• Function：
• domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,

• Subcellular Location：
• Cytoplasm . Membrane ; Peripheral membrane protein .

• Expression：
• Mainly expressed in brain and kidney.

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs