• Target：
• Integrin β5

• Fields：
• >>Phagosome;>>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Proteoglycans in cancer;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy

• Gene Name：
• ITGB5

• Protein Name：
• Integrin beta-5

• Human Gene Id：
• 3693

• Human Swiss Prot No：
• P18084

• Mouse Gene Id：
• 16419

• Mouse Swiss Prot No：
• O70309

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human Integrin beta5. AA range:721-770

• Specificity：
• Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ITGB5;Integrin beta-5

• Observed Band(KD)：
• 88kD

• Background：
• function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,

• Function：
• function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Brain,Kidney,Thymic epithelium,

Shear stress with appropriate time‐step and amplification enhances endothelial cell retention on vascular grafts. Journal of Tissue Engineering and Regenerative Medicine J Tissue Eng Regen M. 2017 Nov;11(11):2965-2978 Human HUVECs

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