IL-13Rα2 Polyclonal Antibody

  • Catalog No.：YT2314
  • Applications：WB;ELISA
  • Reactivity：Human;Rat;Mouse;
    • Target：
    • IL-13Rα2
    • Fields：
    • >>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway
    • Gene Name：
    • IL13RA2
    • Protein Name：
    • Interleukin-13 receptor subunit alpha-2
    • Human Gene Id：
    • 3598
    • Human Swiss Prot No：
    • Q14627
    • Mouse Swiss Prot No：
    • O88786
    • Immunogen：
    • The antiserum was produced against synthesized peptide derived from human IL13RA2. AA range:315-364
    • Specificity：
    • IL-13Rα2 Polyclonal Antibody detects endogenous levels of IL-13Rα2 protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • IL13RA2;IL13R;Interleukin-13 receptor subunit alpha-2;IL-13 receptor subunit alpha-2;IL-13R subunit alpha-2;IL-13R-alpha-2;IL-13RA2;Interleukin-13-binding protein;CD antigen CD213a2
    • Observed Band(KD)：
    • 50kD
    • Background：
    • The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008],
    • Function：
    • domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Binds as a monomer with high affinity to interleukin 13 (IL13), but not to IL4.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,similarity:Contains 1 fibronectin type-III domain.,
    • Subcellular Location：
    • Membrane; Single-pass type I membrane protein.
    • Expression：
    • Brain,Lung,Prostate,Renal cell carcinoma,Testis,

    Attributes

    • Code：
    • YT2314
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-07-19
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