• Target：
• ICAM-2

• Fields：
• >>Cell adhesion molecules;>>Natural killer cell mediated cytotoxicity

• Gene Name：
• ICAM2

• Protein Name：
• Intercellular adhesion molecule 2

• Human Gene Id：
• 3384

• Human Swiss Prot No：
• P13598

• Mouse Swiss Prot No：
• P35330

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human ICAM2. AA range:151-200

• Specificity：
• ICAM-2 Polyclonal Antibody detects endogenous levels of ICAM-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• ICAM2;Intercellular adhesion molecule 2;ICAM-2;CD antigen CD102

• Observed Band(KD)：
• 30kD

• Background：
• The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.,online information:ICAM-2,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,

• Subcellular Location：
• Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Co-localizes with RDX, EZR and MSN in microvilli. .

• Expression：
• Aorta endothelial cell,Blood,Brain,Endothelial cell,Plasma,Spleen,

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