• Target：
• HIBADH

• Fields：
• >>Valine, leucine and isoleucine degradation;>>Metabolic pathways

• Gene Name：
• HIBADH

• Protein Name：
• 3-hydroxyisobutyrate dehydrogenase mitochondrial

• Human Gene Id：
• 11112

• Human Swiss Prot No：
• P31937

• Mouse Gene Id：
• 58875

• Mouse Swiss Prot No：
• Q99L13

• Rat Gene Id：
• 63938

• Rat Swiss Prot No：
• P29266

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human HIBADH. AA range:281-330

• Specificity：
• HIBADH Polyclonal Antibody detects endogenous levels of HIBADH protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HIBADH;3-hydroxyisobutyrate dehydrogenase; mitochondrial;HIBADH

• Molecular Weight(Da)：
• 35kD

• Background：
• This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011],

• Function：
• catalytic activity:3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.,similarity:Belongs to the 3-hydroxyisobutyrate dehydrogenase family.,subunit:Homodimer.,

• Subcellular Location：
• Mitochondrion.

• Expression：
• Detected in skin fibroblasts.

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