• Target：
• Hepatic Lipase

• Fields：
• >>Glycerolipid metabolism;>>Metabolic pathways;>>Cholesterol metabolism

• Gene Name：
• LIPC

• Protein Name：
• Hepatic triacylglycerol lipase

• Human Gene Id：
• 3990

• Human Swiss Prot No：
• P11150

• Mouse Swiss Prot No：
• P27656

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LIPC. AA range:301-350

• Specificity：
• Hepatic Lipase Polyclonal Antibody detects endogenous levels of Hepatic Lipase protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LIPC;HTGL;Hepatic triacylglycerol lipase;HL;Hepatic lipase;Lipase member C

• Observed Band(KD)：
• 56kD

• Background：
• LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.,disease:Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].,function:Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,similarity:Contains 1 PLAT domain.,

• Subcellular Location：
• Secreted .

• Expression：
• Donated clones,Liver,Thymus,

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