Gγ 5 Polyclonal Antibody
- Catalog No.:YT2097
- Applications:IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- Gγ 5
- Fields:
- >>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer
- Gene Name:
- GNG5
- Protein Name:
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
- Human Gene Id:
- 2787
- Human Swiss Prot No:
- P63218
- Mouse Gene Id:
- 1.00044e+008
- Mouse Swiss Prot No:
- Q80SZ7
- Rat Gene Id:
- 1.0036e+008
- Rat Swiss Prot No:
- P63219
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59
- Specificity:
- Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- GNG5;GNGT5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
- Molecular Weight(Da):
- 7kD
- Background:
- G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010],
- Function:
- function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma.,
- Subcellular Location:
- Cell membrane ; Lipid-anchor ; Cytoplasmic side .
- Expression:
- Brain,Platelet,Umbilical cord blood,
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of A549 cells, using GNG5 Antibody. The picture on the right is blocked with the synthesized peptide.