GSK3α Polyclonal Antibody

    • Catalog No.:YT2080
    • Applications:WB;IHC;IF;IP;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • GSK3α
      • Fields:
      • >>Chemokine signaling pathway;>>Dopaminergic synapse;>>Non-alcoholic fatty liver disease;>>Shigellosis
      • Gene Name:
      • GSK3A
      • Protein Name:
      • Glycogen synthase kinase-3 alpha
      • Human Gene Id:
      • 2931
      • Human Swiss Prot No:
      • P49840
      • Mouse Swiss Prot No:
      • Q2NL51
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human GSK3A. AA range:10-59
      • Specificity:
      • GSK3α Polyclonal Antibody detects endogenous levels of GSK3α protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A
      • Observed Band(KD):
      • 51kD
      • Background:
      • glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],
      • Function:
      • catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
      • Subcellular Location:
      • mitochondrion,cytosol,beta-catenin destruction complex,postsynapse,
      • Expression:
      • Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis,
      • Products Images
      • Western Blot analysis of various cells using GSK3α Polyclonal Antibody
      • Western Blot analysis of Jurkat cells using GSK3α Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GSK3 alpha Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from K562, HepG2, and RAW264.7 cells, using GSK3 alpha Antibody. The lane on the right is blocked with the synthesized peptide.