GROγ Polyclonal Antibody

    • Catalog No.：YT2075
    • Applications：IHC;IF;ELISA
    • Reactivity：Human;Rat;Mouse;
      • Target：
      • GROγ
      • Fields：
      • >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>NF-kappa B signaling pathway;>>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>TNF signaling pathway;>>Alcoholic liver disease;>>Epithelial cell signaling in Helicobacter pylori infection;>>Legionellosis;>>Amoebiasis;>>Kaposi sarcoma-associated herpesvirus infection;>>Rheumatoid arthritis;>>Lipid and atherosclerosis
      • Gene Name：
      • CXCL3
      • Protein Name：
      • C-X-C motif chemokine 3
      • Human Gene Id：
      • 2921
      • Human Swiss Prot No：
      • P19876
      • Mouse Swiss Prot No：
      • Q6W5C0
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human GROgamma. AA range:58-107
      • Specificity：
      • GROγ Polyclonal Antibody detects endogenous levels of GROγ protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • CXCL3;GRO3;GROG;SCYB3;C-X-C motif chemokine 3;GRO-gamma(1-73);Growth-regulated protein gamma;GRO-gamma;Macrophage inflammatory protein 2-beta;MIP2-beta
      • Molecular Weight(Da)：
      • 11kD
      • Background：
      • This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014],
      • Function：
      • function:Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.,online information:CXCL3 entry,PTM:N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
      • Subcellular Location：
      • Secreted.
      • Expression：
      • Histiocytic lymphoma,Lung,Peripheral blood monocyte,Placenta,
      • Products Images
      • Immunohistochemistry analysis of GROα antibody in paraffin-embedded human heart tissue.

      Attributes

      • Code：
      • YT2075
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-11-24
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